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Ethan J. Alvarée

Health

I keep a public ledger of my own health data: bloodwork, bone density, body composition, medical and dental records, genetics, prescriptions, supplements, vaccines, and the daily protocols behind them. Every measurement is dated. The latest bloodwork draw is from Jul 2026, and the latest bone scans are from Aug 2026.

These are personal records, not medical advice.

At a glance

The latest result in every area, as of Oct 13, 2026. Each card opens its section.

What I am working on

  • Low bone density for my age: spine Z-score −3.1 and hip −2.0 to −2.1 on the August 2026 clinical scan
  • Chronic lower back, shoulder, and neck pain
  • Borderline high liver enzymes (AST and ALT)Latest: ALT 21 U/L, Jul 2026 optimal; AST 29 U/L, Jul 2026 optimal
  • High cortisolLatest: Cortisol 11 µg/dL, Jul 2026 optimal
  • High SHBGLatest: SHBG 51 nmol/L, Jul 2026 high
  • High HbA1c (against my personal target; still within the lab range)Latest: HbA1c 5.2 %, Jul 2026 optimal
  • Graying hair in my beard
  • Deviated septum, with an average of 48 minutes of snoring a night

Coming up

Follow-ups my doctors have asked for, from Dr. Bradley S. Rosen's plan and the other records.

  1. OpenCancer genetics consult for the family history of colon cancerReferral, Jan 2026
  2. NowEndocrinology consult (booked Oct 14) and the bone-loss labs it ordersDoctor's plan, Aug 2026
  3. NowENT visit to look at the vocal cords (new hoarseness)Referral, Oct 2026
  4. Every 2 weeksAllergy shots, next on Oct 15Sharp injection clinic
  5. By Jan 2027Recheck the lipid panel after easing off the statinDoctor's plan
  6. Aug 2027Repeat the clinical DEXA scan, same scannerDoctor's plan
  7. Oct 2027Tdap booster (ten years after the last)Vaccine record
  8. Apr 2031Next colonoscopy (5 years, for the family history)Colonoscopy report

Timeline

Every dated record on this page in one list: 76 entries since Jan 2015, newest first.

  1. Oct 13, 2026Allergy shot follow-up · Sharp allergy (video)
  2. Aug 6, 2026Clinical bone density scan (spine and hip) · Sharp Rees-Stealy
  3. Aug 4, 2026Longevity and preventive-health visit · Dr. Bradley S. Rosen
  4. Aug 3, 2026Whole-body DEXA scan · BodySpec
  5. Jul 20, 2026Blood draw · 51 markers
  6. Apr 2, 2026Colonoscopy · Sharp endoscopy
  7. Apr 1, 2026Dental cleaning
  8. Apr 1, 2026OralDNA gum-bacteria test
  9. Jan 5, 2026Primary care visit · Sharp primary care
  10. Nov 25, 2025Dental cleaning
  11. Nov 25, 2025OralDNA gum-bacteria test
  12. Oct 30, 2025Covid-19
Show all 76
  1. Oct 30, 2025Influenza
  2. Aug 6, 2025Dental cleaning
  3. Aug 6, 2025OralDNA gum-bacteria test
  4. Jun 6, 2025Dental exam and cleaning
  5. Jun 6, 2025OralDNA gum-bacteria test
  6. Mar 12, 2025Dental cleaning
  7. Mar 12, 2025OralDNA gum-bacteria test
  8. Jan 24, 2025Influenza
  9. Jan 14, 2025Eye exam, contact lens prescription
  10. Dec 20, 2024Blood draw · 22 markers
  11. Dec 20, 2024Allergy consultation and retesting · Sharp allergy
  12. Dec 10, 2024Dental cleaning
  13. Dec 10, 2024OralDNA gum-bacteria test
  14. Sep 18, 2024Dental cleaning
  15. Sep 18, 2024OralDNA gum-bacteria test
  16. Aug 13, 2024Hepatitis B
  17. Aug 13, 2024Influenza
  18. Aug 5, 2024Annual physical · Sharp primary care
  19. Jul 11, 2024Dental cleaning
  20. May 25, 2024Whole-body DEXA scan · Dexa Body
  21. May 20, 2024Blood draw · 88 markers
  22. Apr 4, 2024Dental exam and cleaning
  23. Mar 8, 2024Allergy shots, every 2 to 6 weeks · Sharp allergy
  24. Nov 6, 2023Hearing test · normal
  25. Oct 5, 2023Covid-19
  26. Oct 3, 2023Blood draw · 7 markers
  27. Sep 27, 2023Influenza
  28. Sep 14, 2023Blood draw · 51 markers
  29. May 26, 2023Right foot X-ray · Sharp radiology
  30. May 12, 2023Blood draw · 59 markers
  31. Jan 31, 2023First longevity visit · Dr. Rosen
  32. Jan 9, 2023Blood draw · 2 markers
  33. Dec 23, 2022Covid-19
  34. Dec 23, 2022Influenza
  35. Dec 14, 2022Blood draw · 49 markers
  36. Dec 1, 2022Influenza
  37. Sep 20, 2022Orthopoxvirus
  38. Sep 2, 2022Covid-19
  39. Sep 2, 2022Influenza
  40. Jul 20, 2022Orthopoxvirus
  41. Jun 10, 2022Fire ant reaction review · Sharp allergy
  42. Dec 10, 2021Allergy testing · Sharp allergy
  43. Oct 25, 2021Covid-19
  44. Oct 11, 2021Influenza
  45. Apr 1, 2021Covid-19
  46. Mar 3, 2021Covid-19
  47. Nov 20, 2020Sore throat after a COVID exposure · Sharp
  48. Oct 19, 2020Blood draw · 9 markers
  49. Oct 19, 2020Influenza
  50. Feb 12, 2020Blood draw · 9 markers
  51. Feb 12, 2020Influenza
  52. Oct 6, 2017Influenza
  53. Oct 6, 2017Td, Tdap
  54. May 31, 2017Eye exam, glasses prescription
  55. Dec 7, 2016Itchy rash · UCSD Student Health
  56. Aug 12, 2016Blood draw · 36 markers
  57. Aug 12, 2016HPV
  58. Aug 10, 2016Rectal bleeding · UCSD Student Health
  59. Feb 18, 2016Blood draw · 35 markers
  60. Feb 17, 2016Watery stools · UCSD Student Health
  61. Jan 13, 2016Blood draw · 35 markers
  62. Jan 13, 2016HPV
  63. Dec 1, 2015HPV
  64. Jan 2, 2015Influenza

Bone density

Bone density is the main thing I am working on. The clinical spine and hip scan from Aug 6, 2026 is the one that counts; the two whole-body scans add a rough total-body score.

Lumbar spine (L1–L4)
−3.1Z-score
0.857 g/cm² · T −2.7
Below the expected range for age
Femoral neck (left)
−2.1Z-score
0.780 g/cm²
Below the expected range for age
Total hip (left)
−2.0Z-score
0.787 g/cm²
Below the expected range for age
  • Below the expected range for age (−2.0 or lower)
  • Low end of the expected range
  • Expected for age (−1.0 or higher)
  • Lumbar spine (L1–L4)
    diagnostic site
    −3.1 · 0.857 g/cm²below the expected range for age
  • Vertebra L1
    part of L1–L4
    −3.2 · 0.784 g/cm²below the expected range for age
  • Vertebra L2
    part of L1–L4
    −2.7 · 0.919 g/cm²below the expected range for age
  • Vertebra L3
    part of L1–L4
    −2.6 · 0.935 g/cm²below the expected range for age
  • Vertebra L4
    part of L1–L4
    −3.6 · 0.795 g/cm²below the expected range for age
  • Femoral neck (left)
    diagnostic site
    −2.1 · 0.780 g/cm²below the expected range for age
  • Total hip (left)
    diagnostic site
    −2.0 · 0.787 g/cm²below the expected range for age
  • Total body, Aug 2026
    BodySpec
    −1.4 · 1.060 g/cm²screening estimate
  • Total body, May 2024
    Dexa Body
    −0.6screening estimate

Z-score: standard deviations from the average for my age and sex. For men under 50 this is the score clinicians use.

How to read these numbers

  • For men under 50, the International Society for Clinical Densitometry says to read the Z-score, which compares bone density with people of the same age and sex. A Z-score of −2.0 or lower is “below the expected range for age.” Osteopenia and osteoporosis are T-score categories written for people over 50, and under 50 osteoporosis is not diagnosed from bone density alone.
  • Fracture risk rises about 1.5-fold for each standard deviation of lower bone density (about 2.6-fold at the hip), which is why scores between −1.0 and −2.0 show as the low end of the expected range.
  • Only the lumbar spine and the hip (sometimes the forearm) are used for diagnosis. The total-body score from a body composition scan is a rough screen: it includes the dense skull, and GE Lunar adjusts its Z-score for body weight. That is how the whole-body scans read −0.6 and −1.4 while the spine read −3.1.
  • The three scans came from three machines at three sites, and readings from different machines are not compared directly. On the same machine, a spine change has to be about 5% before it counts as real, so the next clinical scan on the same scanner is the one to compare with this one.

Sources: ISCD 2023 adult official positions · Marshall et al. 1996, BMJ · ISCD precision and least significant change · University of Washington: reading a DEXA report

Body composition

Whole-body DEXA scans from Dexa Body (May 2024) and BodySpec (Aug 2026). Changes are shown against the first scan.

Body fat
17.2%
+3.4 pts since May 2024
Fat ÷ total mass, same basis for every scan
on targettarget 8–19.9%
Lean mass
93.5lb
−0.2 lb since May 2024
Muscle, organs, water
Fat mass
20.3lb
+4.6 lb since May 2024
Total mass 118.3 lb
Visceral fat
0.37lb
+0.21 lb since May 2024
10.9 in³ around the organs
on targettarget under 1.1 lb
Appendicular lean mass index
7.58kg/m²
+0.37 since May 2024
Arm and leg lean mass ÷ height², calculated
below targettarget 9.8 or more
Android/gynoid ratio
0.81
+0.20 since May 2024
Belly fat vs. hip fat
on targettarget 1.0 or less
What I weigh, by tissue
  • Lean
  • Fat
  • Bone
  • May 2024 · Dexa Body113.9 lb total
    lean 93.7 · fat 15.7 · bone 4.5 (bone derived: total minus lean and fat)
  • Aug 2026 · BodySpec118.3 lb total
    lean 93.5 · fat 20.3 · bone 4.4

By region

Head: not reportedTrunk: 43.9 lbRight arm: 5.2 lbLeft arm: 4.9 lbRight leg: 16.6 lbLeft leg: 16.1 lb
Lean mass (lb), BodySpec, Aug 2026. Darker means more. Front view.
RegionMay 2024Aug 2026Change
Right arm5.15.2+0.1
Left arm5.54.9−0.6
Trunk46.043.9−2.1
Right leg15.416.6+1.2
Left leg14.716.1+1.4
Android (belly)6.46.9+0.5
Gynoid (hips, thighs)13.814.0+0.2

Pounds of tissue as printed by each report. Two different scanners and sites, so treat changes under about 1 lb as noise.

Blood pressure and weight

Every blood pressure on record, from student-health visits in 2016 to the dental chair and the colonoscopy suite in 2026.

Latest 113/71 mmHg, Apr 2, 2026 · normal

18 readings

608010012014020162017201820192020202120222023202420252026Jan 13, 2016: 115/80 mmHg, pulse 77 (stage 1 high, UCSD)Jan 16, 2016: 119/81 mmHg, pulse 70 (stage 1 high, UCSD)Jan 20, 2016: 111/75 mmHg, pulse 72 (normal, UCSD)Feb 17, 2016: 124/79 mmHg, pulse 100 (elevated, UCSD)Aug 10, 2016: 115/86 mmHg, pulse 110 (stage 1 high, UCSD)Aug 23, 2016: 116/70 mmHg, pulse 61 (normal, UCSD)Dec 7, 2016: 122/77 mmHg, pulse 72 (elevated, UCSD)Feb 12, 2020: 100/60 mmHg (normal, self-reported)Oct 19, 2020: 90/60 mmHg (normal, self-reported)Dec 10, 2021: 100/67 mmHg (normal, self-reported)Jan 9, 2023: 112/82 mmHg (stage 1 high, self-reported)Aug 5, 2024: 106/64 mmHg, pulse 66 (normal, Sharp physical)Jun 6, 2025: 97/61 mmHg, pulse 55 (normal, dental office)Aug 6, 2025: 118/72 mmHg (normal, dental office)Nov 25, 2025: 113/86 mmHg, pulse 59 (stage 1 high, dental office)Jan 5, 2026: 100/62 mmHg, pulse 60 (normal, Sharp primary care)Apr 1, 2026: 112/85 mmHg, pulse 57 (stage 1 high, dental office)Apr 2, 2026: 113/71 mmHg, pulse 69 (normal, Sharp endoscopy)

Each bar runs from the bottom number (diastolic) to the top (systolic). Lines at 80 and 120 mmHg mark the normal limits; green is normal, amber elevated or stage 1, red stage 2 (ACC/AHA 2017).

Every reading
DatemmHgPulseCategoryWhere
Apr 2, 2026113/7169normalSharp endoscopy
Apr 1, 2026112/8557stage 1 highdental office
Jan 5, 2026100/6260normalSharp primary care
Nov 25, 2025113/8659stage 1 highdental office
Aug 6, 2025118/72normaldental office
Jun 6, 202597/6155normaldental office
Aug 5, 2024106/6466normalSharp physical
Jan 9, 2023112/82stage 1 highself-reported
Dec 10, 2021100/67normalself-reported
Oct 19, 202090/60normalself-reported
Feb 12, 2020100/60normalself-reported
Dec 7, 2016122/7772elevatedUCSD
Aug 23, 2016116/7061normalUCSD
Aug 10, 2016115/86110stage 1 highUCSD
Feb 17, 2016124/79100elevatedUCSD
Jan 20, 2016111/7572normalUCSD
Jan 16, 2016119/8170stage 1 highUCSD
Jan 13, 2016115/8077stage 1 highUCSD

Weight and BMI at clinic visits

  • Apr 2, 2026112 lbBMI 19.9
  • Jan 5, 2026115 lbBMI 20.5
  • Aug 5, 2024113.4 lbBMI 20.2
  • Jan 31, 2023108 lbBMI 19.1
  • Dec 7, 2016114.4 lbBMI 19.9
  • Aug 23, 2016115 lbBMI 20.4
  • Aug 10, 2016112.4 lbBMI 19.6
  • Feb 17, 2016110 lbBMI 19.2
  • Jan 20, 2016113.8 lbBMI 19.8
  • Jan 13, 2016110 lbBMI 19.2

Clinic readings unless marked self-reported. The UCSD pulse of 110 in Aug 2016 came at a visit for a painful problem; the intake-form pulse of 54 is a resting rate from a watch. Height measures 5 ft 2.8 in at Sharp. Scan weights are in Body composition above.

Bloodwork

13 draws since 2016, from InsideTracker, Ulta Lab Tests, Sharp and UCSD Student Health, each result graded against an evidence-based optimal band rather than the lab's population range. On May 20, 2024 two services drew the same morning; where both measured a marker, the InsideTracker result is shown.

Latest draw · Jul 20, 2026

51 markers graded

  • 49
    Optimal
  • 1
    Suboptimal
  • 1
    Out of range

Worth a look in the latest draw

Not retested since

Older results outside their optimal band. The Jul 2026 panel did not include these markers, so each one shows the last time it was measured.

Green is the evidence-based optimal band. Yellow is outside optimal but not yet a problem. Red is outside the lab's range, or past a level that outcome studies tie to risk. Open a marker for every result, the reasoning behind its band, and the sources. Each marker is graded against one range, the current lab's, so an old result from a different lab can read differently from its own report.

All 13 draws, 2016 to 2026
  • Jul 20, 2026InsideTracker
  • Dec 20, 2024Sharpreport (PDF)
  • May 20, 2024InsideTracker and Ulta Lab Tests
  • Oct 3, 2023Sharp
  • Sep 14, 2023InsideTracker
  • May 12, 2023InsideTracker and Ulta Lab Tests
  • Jan 9, 2023Sharp
  • Dec 14, 2022InsideTracker
  • Oct 19, 2020Sharpreport (PDF)
  • Feb 12, 2020Sharpreport (PDF)
  • Aug 12, 2016UCSD Student Health
  • Feb 18, 2016UCSD Student Health
  • Jan 13, 2016UCSD Student Health

Cardiovascular

9 optimal9 markers
MarkerLatestStatusOptimal and lab rangeTrend
38 mg/dLoptimaloptimal ≤ 59 · lab ≤ 90
94 mg/dLoptimaloptimal ≤ 199 · lab ≤ 200
48 mg/dLoptimaloptimal 40–96 · lab ≥ 40
37 mg/dLoptimaloptimal ≤ 54 · lab ≤ 100
70 mg/dLDec 2024optimaloptimal ≤ 84 · lab ≤ 130
2.6 Dec 2024optimallab ≤ 5
< 10 nmol/LMay 2023optimaloptimal ≤ 75 · lab ≤ 75no chart: results reported as detection limits, listed in the expanded row
3.1 uMMay 2023optimaloptimal ≤ 6.1 · lab ≤ 6.2
30 mg/dLoptimal↗ closer to targetoptimal ≤ 99 · lab ≤ 150

Glucose monitor

A month on a continuous glucose monitor, winter 2022 to 2023: the readout that pairs with fasting glucose and HbA1c above.

Dexcom G6, Nov 29, 2022 to Dec 30, 2022: 31 of 32 days of data.

Average
112mg/dL
Time in range
99%70 to 180 mg/dL
GMI
6.0%estimated A1c
Variability
17.9%CV; under 36% is stable

Under 1% of readings were high and under 1% low. The lab HbA1c that month was 5%, lower than the monitor's estimate; gaps like this are common, and the lab value is the one guidelines use.

A day in detail, Dec 2022: 428 readings over 1.5 days

7010014018022012 AM6 AM12 PM6 PM11 PM0:00: average 96 mg/dL, middle half 88 to 104, range 78 to 1081:00: average 103 mg/dL, middle half 100 to 108, range 91 to 1102:00: average 96 mg/dL, middle half 95 to 97, range 89 to 1063:00: average 97 mg/dL, middle half 92 to 99, range 91 to 1094:00: average 98 mg/dL, middle half 96 to 105, range 79 to 1085:00: average 97 mg/dL, middle half 90 to 106, range 83 to 1076:00: average 101 mg/dL, middle half 99 to 104, range 97 to 1067:00: average 95 mg/dL, middle half 94 to 101, range 74 to 1078:00: average 97 mg/dL, middle half 86 to 110, range 78 to 1149:00: average 91 mg/dL, middle half 81 to 100, range 75 to 10910:00: average 86 mg/dL, middle half 83 to 88, range 75 to 9311:00: average 79 mg/dL, middle half 78 to 81, range 76 to 8512:00: average 82 mg/dL, middle half 81 to 82, range 81 to 8413:00: average 82 mg/dL, middle half 80 to 85, range 79 to 8514:00: average 82 mg/dL, middle half 79 to 86, range 79 to 9415:00: average 75 mg/dL, middle half 69 to 81, range 69 to 9516:00: average 95 mg/dL, middle half 93 to 97, range 92 to 9917:00: average 125 mg/dL, middle half 96 to 159, range 94 to 17418:00: average 154 mg/dL, middle half 141 to 170, range 136 to 17619:00: average 196 mg/dL, middle half 177 to 216, range 151 to 22120:00: average 182 mg/dL, middle half 174 to 195, range 166 to 20521:00: average 124 mg/dL, middle half 93 to 157, range 91 to 16522:00: average 99 mg/dL, middle half 96 to 101, range 94 to 10423:00: average 88 mg/dL, middle half 82 to 94, range 77 to 95

Line: hourly average. Shading: the middle half of readings. Green band: the 70 to 180 mg/dL target. Flat around 80 to 105 all night and day, with one rise after the evening meal (4 to 8 PM eating window) that peaks near 200 and is back near 100 by 10 PM.

Doctor’s plan

The priorities from my latest longevity and preventive-health visit.

Dr. Bradley S. Rosen · biogerontology, lipidology, and preventive health · visit of Aug 4, 2026

Labs remain excellent across the board and cardiovascular risk is about as low as it gets. The biggest modifiable risk over the coming decades is bone density.

Bone density

  • Endocrinology or osteoporosis consult, with a formal bone density test to check the DEXA scans
  • Labs for secondary causes of bone loss: PTH, calcium, phosphorus, magnesium, vitamin D, TSH, testosterone, estradiol, and possibly a celiac panel
  • Resistance and weight-bearing training aimed at loading bone

Statin

  • Ease off atorvastatin (from three times to twice a week, or a lower dose), keep ezetimibe at 5 mg most days
  • Accept a deliberate rise in LDL and ApoB, then recheck the lipid panel in 10 weeks to 5 months

Supplements

  • Simplify the stack: drop some, cycle others instead of taking them daily
  1. This monthLower the statin, book the bone consult, order bone labs, trim supplements
  2. 10 weeks to 5 monthsRecheck the lipid panel
  3. 12 monthsRepeat DEXA
The first visit's plan, Jan 2023
  • Keep the plant-based diet
  • Lower LDL and ApoB from the mid-50s toward the mid-30s mg/dL or lower
  • A low-dose statin in the evening 2 to 3 times a week; hold off on ezetimibe for now
  • Start monitoring blood pressure
  • Build acarbose from 25 mg toward 50 to 75 mg a day
  • Psyllium husk, 2 teaspoons every day for life
  • At least 400, ideally 500, minutes of exercise a week, about 20% high intensity
  • Rucking, building to 30 to 40 lb, for bone density
  • Morning sunlight; daily sunscreen and regular skin checks
  • More spermidine-rich vegetables, whole fresh fruit, grains and cereals
  • Methyl B vitamins 2 to 3 times a week
  • Read up on urolithin A, alpha-ketoglutarate and low-dose lithium orotate
  • Stop grapefruit juice with weekly rapamycin, so each dose is a sharp pulse
  • Weigh rapamycin and metformin against fertility: pause, limit to about 3 years, or bank sperm if children are planned soon
  • Hold off on canagliflozin because of possible effects on bone density
  • First colonoscopy at 35

Labs ordered: TSH, Lipoprotein(a), Fasting insulin, C-peptide.

Conditions

Everything on my problem lists since 2016, in plain words: 11 current or watched, the rest resolved.

Active · 8

  • Low bone density for agesince May 2024

    First seen on a whole-body DEXA in May 2024 and confirmed on the clinical scan in Aug 2026. Dr. Rosen put it in the bottom 10 percent for age and sex if the scans are accurate, and called it the biggest modifiable risk for the decades ahead.

  • Mixed hyperlipidemiasince Jan 2026

    The chart label for the lipid treatment. On atorvastatin and ezetimibe, ApoB and LDL sit far below the plaque threshold.

  • Allergic rhinitis: outdoor mold and grassessince childhood

    Year-round with seasonal flares, since childhood in Michigan. On allergy shots since 2021, plus a steroid nasal spray.

  • Stinging-insect venom allergysince childhood

    A whole-body reaction to a bee sting as a child, charted as anaphylaxis. On venom shots since about 2022, with no stings since.

  • Throat reflux (LPR) and vocal cord dysfunctionsince Dec 2021

    Charted in Dec 2021. New, frequent hoarseness in Oct 2026, not thought to be reflux, led to an ENT referral to look at the vocal cords.

  • Deviated septum and enlarged nasal turbinatessince Nov 2023

    Charted in Nov and Dec 2023; a likely contributor to nightly snoring.

  • Chronic low back painsince May 2023

    Since a deadlift strain in Oct 2022.

  • Family history of colon cancersince Jan 2026

    The reason for a first colonoscopy at 34 and a 5-year repeat, and for a referral to cancer genetics.

Watching · 3

  • Impaired glucose tolerancesince Jan 2023

    Charted in Jan 2023, the reason acarbose and metformin are on the list. Every HbA1c since has been under 5.7%, and a month on a glucose monitor stayed 99% in range.

  • Periodontitissince Jun 2025

    Managed with cleanings every three months and saliva tests; charted as healthy gums at each cleaning since Aug 2025.

  • Small internal hemorrhoidssince Aug 2016

    Bleeding hemorrhoids in 2016, treated with cream and more fiber; seen as small and quiet on the 2026 colonoscopy.

Resolved · 7

  • Right-ear tinnitussince Mar 2023

    Ringing, fullness and an earache in the right ear in spring 2023 that faded on their own; the Nov 2023 hearing test was normal.

  • Skin spots on the necksince Jan 2026

    Three small spots on the left jawline and neck, present 6 to 8 months, frozen off (cryotherapy) on Jan 5, 2026.

  • Suspected glass in the right footsince May 2023

    An X-ray on May 26, 2023 found no foreign body and normal bones and joints.

  • Fire ant bitessince Jun 2022

    A whole-body itchy rash with swelling after many bites, judged not anaphylaxis; no fire ant shots needed and venom IgE was undetectable in 2024.

  • Sore throat after a COVID exposuresince Nov 2020

    Rapid and lab strep tests and a COVID PCR were all negative.

  • Itchy rash (contact dermatitis)since Dec 2016

    Red, itchy bumps after new body lotions, in someone with past eczema; cleared with an antihistamine and gentler soap.

  • Watery stoolssince Feb 2016

    Stool culture, three parasite tests, a celiac blood screen and a blood count were all negative.

Colonoscopy

My first colonoscopy, early because of family history.

The entire colon looked normal.

Screening, for a family history of colon cancer · age 34 · Apr 2, 2026

  • Colon

    Normal

    The entire colon looked normal: no polyps, growths or inflammation, and nothing removed

  • Hemorrhoids

    Small, internal

    Very common; need nothing unless they bleed or bother

  • Pathology

    None needed

    No specimens were taken

Reached
CecumThe very start of the large intestine, so the whole colon was seen
Bowel prep
9 of 9Boston Bowel Preparation Scale, 3 in each segment: fully clean
Withdrawal
About 12 minLooking time on the way out, from the scope times; the benchmark is at least 6 minutes
Sedation
ModerateFentanyl 50 mcg and midazolam 4 mg; no complications

A long, twisty colon made the exam moderately difficult, so the team pressed on the abdomen to help the scope along. That is common and not a disease. The PDF adds the findings diagram and 15 of the 17 photos through the scope, cecum to rectum, all normal.

Next colonoscopy: Apr 2031. A clean colonoscopy usually means 10 years until the next one; the family history shortens it to 5, the standard for a close relative diagnosed young.

Allergies

Outdoor mold, grasses and stinging-insect venom, treated with allergy shots. No drug, food or latex allergies.

Allergy shots build tolerance by giving rising, then steady, doses of what you react to. Mine treat two things: grasses and outdoor molds since 2021, and stinging-insect venom since about 2022.

Environmental shots
Since 2021Grasses and molds; nearly 3 years on maintenance by Dec 2024; symptoms much better
Venom shots
Since about 2022For a childhood whole-body reaction to a bee sting; spaced to every 6 weeks
Clinic visits
46Mar 2024 to Aug 2026 in the Sharp record, each with 30 minutes of observation and no reactions
Stings since starting
NonePlan: continue the shots indefinitely
  • Fluticasone nasal spray daily and azelastine nasal spray as needed (Dec 2024 plan); a nasal spray and an oral antihistamine in use as of Oct 2026
  • No drug, food or latex allergies

Specific IgE blood test, Dec 20, 2024: 55 allergens, 13 with a measurable level. The ring marks the Dec 2021 result, before most of the immunotherapy.

  • Alternaria alternatamold4.49 kU/L · class 3, highDec 2021: 8.69
  • Bipolarismold0.53 kU/L · class 1, lowDec 2021: 0.24
  • Bahia grasspollen0.46 kU/L · class 1, lowDec 2021: 0.93
  • Kentucky bluegrasspollen0.40 kU/L · class 1, lowDec 2021: 0.82
  • Epicoccum purpurascensmold0.38 kU/L · class 1, lowDec 2021: 0.35
  • Johnson grasspollen0.35 kU/L · class 1, lowDec 2021: 0.41
  • Orchard grasspollen0.29 kU/L · class 0/1, unclearDec 2021: 0.58
  • Perennial ryegrasspollen0.28 kU/L · class 0/1, unclearDec 2021: 0.54
  • Bermuda grasspollen0.25 kU/L · class 0/1, unclearDec 2021: 0.30
  • Timothy grasspollen0.21 kU/L · class 0/1, unclearDec 2021: 0.64
  • Western ragweedpollen0.18 kU/L · class 0/1, unclearDec 2021: 0.13
  • Honey bee venomvenom0.14 kU/L · class 0/1, unclear
  • Fusarium (Gibberella)mold0.11 kU/L · class 0/1, unclearDec 2021: 0.14
  • Box elderpollen<0.10 kU/L · none detectedDec 2021: 0.13
  • Aspergillus fumigatusmold<0.10 kU/L · none detectedDec 2021: 0.12

kU/L on a log scale; the lines are the lab's class boundaries (0.35 low, 0.70 moderate, 3.50 high, 17.5 very high). Under 0.35 is of uncertain significance. A measurable level shows sensitization, which matters only with matching symptoms.

Not detected · Pollen, dander, mites

Acacia, Arizona cypress, Birch, Cat dander, Cocklebur, German cockroach, Cottonwood, Dog dander, Dust mite, D. farinae, Dust mite, D. pteronyssinus, Elm, Eucalyptus, Lamb's quarters (goosefoot), Grey alder, Kochia (firebush), Mesquite, Mulberry, Mustard, Oak, Olive, Pecan/hickory, Pepper tree, Common pigweed, Pine, Russian thistle (saltwort), Lenscale, London plane (maple leaf sycamore), Walnut, White ash, Yellow dock

Not detected · Stinging insects

Paper wasp venom, White-faced hornet venom, Yellow hornet venom, Yellow jacket (common wasp) venom

Not detected · Molds

Chaetomium globosum, Cladosporium herbarum, Mucor racemosus, Penicillium chrysogenum (notatum)

  • Total IgE 29.2 IU/mLDec 2021 · lab range 0 to 158; normal: no sign of a broadly raised allergic state
  • Tryptase 5.6 mcg/LMay 2022 · lab range 10.9 or less; normal baseline mast-cell level, checked before venom shots
  • Fire ant venom IgE <0.10 kU/LDec 2024 · lab range 0.34 or less; none detected

Not run (not enough sample): Mugwort, English plantain (ribwort).

Visits

Medical visits, newest first. Dental visits are in the Dental tab, blood draws in Bloodwork and scans in Body.

  1. Oct 13, 2026Allergy shot follow-upSharp allergy (video)

    Shots going well, no reactions or stings; new hoarseness, so an ENT referral to look at the vocal cords.

  2. Aug 4, 2026Longevity and preventive-health visitDr. Rosen

    Bone density became the top priority; ease off the statin; trim the supplements.

  3. Apr 2, 2026ColonoscopySharp endoscopy

    Entire colon normal; small internal hemorrhoids; repeat in 5 years.

  4. Jan 5, 2026Primary care visitSharp primary care

    Three neck skin spots frozen off; colonoscopy ordered and a cancer-genetics referral for the family history; clinical bone scan ordered; statin refilled.

  5. Dec 20, 2024Allergy consultation and retestingSharp allergy

    Nasal sprays added; allergy and routine blood tests drawn; shots continued.

  6. Aug 5, 2024Annual physicalSharp primary care

    Normal exam. An outside scan suggesting low bone density led to a clinical bone scan order (done in 2026).

  7. Mar 8, 2024Allergy shots, every 2 to 6 weeksSharp allergy

    46 injection visits through Aug 2026 in the record, none with a reaction.

  8. Nov 6, 2023Hearing testSharp audiology

    Normal hearing in both ears.

9 earlier visits, back to 2016
  1. May 26, 2023Right foot X-raySharp radiology

    No glass or other foreign body; normal bones.

  2. Jan 31, 2023First longevity visitDr. Rosen

    Three hours through every biomarker and the DNA results; a low-dose statin, a higher acarbose dose and blood-pressure checks.

  3. Jun 10, 2022Fire ant reaction reviewSharp allergy

    Whole-body skin reaction, not anaphylaxis; no fire ant shots needed.

  4. Dec 10, 2021Allergy testingSharp allergy

    Blood tests found outdoor mold and grass sensitization; allergy shots began that year.

  5. Nov 20, 2020Sore throat after a COVID exposureSharp

    Strep and COVID tests negative.

  6. May 31, 2017Eye examUCSD optometry

    Mild myopia with astigmatism, corrected to 20/20; eye pressure 11 mmHg both eyes; healthy eyes.

  7. Dec 7, 2016Itchy rashUCSD Student Health

    Likely contact dermatitis from new lotions; antihistamine and gentler soap.

  8. Aug 10, 2016Rectal bleedingUCSD Student Health

    Bleeding internal hemorrhoids and constipation; cream, more fiber, and a colorectal referral.

  9. Feb 17, 2016Watery stoolsUCSD Student Health

    Stool, parasite, celiac and blood tests all negative.

Hearing

Normal hearing in both ears

Sharp Rees-Stealy Audiology · Nov 6, 2023

Checked for: a few months of right-ear fullness and rumbling that went away on its own.

Pure-tone thresholds
0 to 15 dB HL250 to 8,000 Hz, both ears; normal is 25 or better
Word recognition
100%both ears, at 45 dB HL
Speech threshold
5 / 0 dB HLright / left
Tympanometry
Type Aboth ears: normal eardrum movement
Otoacoustic emissions
Present1.5 to 6.9 kHz in both ears: healthy outer hair cells

Vision

Contact lenses · Acuvue Oasys for Astigmatism

Prescribed Jan 14, 2025, expired Jan 14, 2026

EyeSphereCylinderAxisBase curveDiameter
Right−0.50−1.25090°8.614.5
Left−0.50−1.25110°8.614.5
  • May 2017 · Glasses, distance: right −0.50 −1.25 × 092, left −0.50 −1.25 × 098. Corrected to 20/20 in each eye; mild myopia with astigmatism.

Dental

Every dental visit since Apr 2024: exams, cleanings every three months, pocket charting, and 7 OralDNA saliva tests for gum-disease bacteria.

Bleeding on probing
0%healthy
of sites, at all 5 charted exams
Pockets 4 mm or less
100%healthy
all 168 sites, at every charted exam
Gum diagnosis
Healthy
since Aug 2025; stage I periodontitis Sep 2024 to Jun 2025
Cleanings
9
since Apr 2024, about every three months

Pocket depths

  • 168 sites
  • average 2.49 mm
  • deepest 3 mm
  • 0 pockets of 5 mm+
Tooth 1 not present323323323322222222222222222222323323323323Tooth 16 not present
Tooth 1 not present323323323323322222222222222222223323323323Tooth 16 not present
RightLeft
Tooth 32 not present333323323323322222222222222223323323333333Tooth 17 not present
Tooth 32 not present333323323323323323323323323323323323333333Tooth 17 not present
2 1 to 3 mm, healthy4 4 mm, worth watching5 5 mm or more, a pocket wisdom tooth not present

Attachment loss recorded this exam: tooth 14, tongue side, 4/4/4 mm.

Gum-disease bacteria

  • Tannerella forsythiaTfhigh risk
    Sep 2024: 8.7K copies/mLDec 2024: 3.4K copies/mLMar 2025: not detectedJun 2025: < 1.7K copies/mLAug 2025: < 1.7K copies/mLNov 2025: < 1.7K copies/mLApr 2026: ~19K copies/mL
    ~19K · below lineline 74K
  • Fusobacterium nucleatumFnmoderate risk
    Sep 2024: 2.19M copies/mL, above the reference lineDec 2024: 1.03M copies/mLMar 2025: 720K copies/mLJun 2025: ~130K copies/mLAug 2025: ~1.80M copies/mL, above the reference lineNov 2025: ~740K copies/mLApr 2026: ~4.40M copies/mL, above the reference line
    ~4.40M above lineline 1.18M
  • Prevotella intermediaPimoderate risk
    Sep 2024: 95K copies/mL, above the reference lineDec 2024: 167K copies/mL, above the reference lineMar 2025: 92K copies/mL, above the reference lineJun 2025: ~160K copies/mL, above the reference lineAug 2025: ~290K copies/mL, above the reference lineNov 2025: ~170K copies/mL, above the reference lineApr 2026: ~370K copies/mL, above the reference line
    ~370K above lineline 71K
  • Campylobacter rectusCrmoderate risk
    Sep 2024: 49K copies/mLDec 2024: 18K copies/mLMar 2025: 7.5K copies/mLJun 2025: ~15K copies/mLAug 2025: ~130K copies/mL, above the reference lineNov 2025: ~12K copies/mLApr 2026: ~32K copies/mL
    ~32K · below lineline 76K
  • Eikenella corrodensEclow risk
    Sep 2024: 39K copies/mLDec 2024: 9.7K copies/mLMar 2025: not detectedJun 2025: not detectedAug 2025: ~13K copies/mLNov 2025: ~9.5K copies/mLApr 2026: ~140K copies/mL, above the reference line
    ~140K above lineline 91K
  • Capnocytophaga speciesCslow risk
    Sep 2024: 434K copies/mL, above the reference lineDec 2024: 148K copies/mLMar 2025: 66K copies/mLJun 2025: ~72K copies/mLAug 2025: ~740K copies/mL, above the reference lineNov 2025: ~200K copies/mLApr 2026: ~870K copies/mL, above the reference line
    ~870K above lineline 427K

Never detected in 7 tests: Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, Eubacterium nodatum, Peptostreptococcus micros.

Genome copies per mL of oral rinse on a log scale from 100 to 10 million, Sep 2024 to Apr 2026. The flat line is the lab's reference, the average level in early gum disease. Hollow points are tests where the bacterium was not detected; values marked ~ are read off the lab's charts.

Every count, test by test
BacteriumSep 2024Routine screeningDec 2024Treatment follow-upMar 2025Routine screeningJun 2025Treatment follow-upAug 2025Treatment follow-upNov 2025Follow-upApr 2026Follow-up
Aggregatibacter actinomycetemcomitansAanot detectednot detectednot detectednot detectednot detectednot detectednot detected
Porphyromonas gingivalisPgnot detectednot detectednot detectednot detectednot detectednot detectednot detected
Tannerella forsythiaTf8.7K3.4Knot detected< 1.7K< 1.7K< 1.7K~19K
Treponema denticolaTdnot detectednot detectednot detectednot detectednot detectednot detectednot detected
Eubacterium nodatumEnnot detectednot detectednot detectednot detectednot detectednot detectednot detected
Fusobacterium nucleatumFn2.19Mabove line1.03M720K~130K~1.80Mabove line~740K~4.40Mabove line
Prevotella intermediaPi95Kabove line167Kabove line92Kabove line~160Kabove line~290Kabove line~170Kabove line~370Kabove line
Campylobacter rectusCr49K18K7.5K~15K~130Kabove line~12K~32K
Peptostreptococcus microsPmnot detectednot detectednot detectednot detectednot detectednot detectednot detected
Eikenella corrodensEc39K9.7Knot detectednot detected~13K~9.5K~140Kabove line
Capnocytophaga speciesCs434Kabove line148K66K~72K~740Kabove line~200K~870Kabove line
  • Sep 2024 · Six of eleven detected; Fn, Pi and Cs above the reference line. Treated after this test.
  • Dec 2024 · Most counts down; Pi, which often resists treatment, still above its line.
  • Mar 2025 · No high-risk bacteria detected; only Pi still above its line.
  • Jun 2025 · Lab: 31% increase since the previous test. Above the line: Pi.
  • Aug 2025 · Lab: 24% increase since the previous test. Above the line: Fn, Pi, Cr, Cs.
  • Nov 2025 · Lab: 6% decrease since the previous test. Above the line: Pi.
  • Apr 2026 · Lab: 18% increase since the previous test. Above the line: Fn, Pi, Ec, Cs.

Genome copies per mL of oral rinse (qPCR), on a log scale from 100 to 10 million. The tick is the lab's reference line, the average level in early gum disease; the lab says it is not a basis for treatment on its own. Exact counts come from the dental record; from June 2025 the reports print only charts, so those values (~) are read off the lab's bars, and < marks a level under the chart's smallest bar.

Active collagenase (aMMP-8), saliva

10ng/mLMar 2025
  1. Optimalunder 10 ng/mL
  2. Borderline10 to 19 ng/mL
  3. Moderate20 to 29 ng/mL
  4. Rapid30 ng/mL or more

A chairside saliva test for active collagenase (aMMP-8), a marker of active gum breakdown. 10 ng/mL sits at the very bottom of the borderline band.

Visits

  1. Apr 1, 2026CleaningHealthy gums

    Hygiene instructions · Cleaning · OralDNA saliva test

    Blood pressure 112/85, pulse 57

  2. Nov 25, 2025CleaningHealthy gums

    Cleaning · OralDNA saliva test

    Blood pressure 113/86, pulse 59

  3. Aug 6, 2025CleaningHealthy gums

    Cleaning · OralDNA saliva test

    Blood pressure 118/72

  4. Jun 6, 2025Exam and cleaningStage I, grade B periodontitis (molar/incisor)

    Periodic exam · X-rays · Bitewing x-rays · Intraoral photos · Cleaning · Laser bacterial decontamination · OralDNA saliva test

    Blood pressure 97/61, pulse 55

  5. Mar 12, 2025CleaningStage I, grade A periodontitis (molar/incisor)

    Hygiene instructions · Cleaning · aMMP-8 saliva screen · OralDNA saliva test

  6. Dec 10, 2024CleaningStage I, grade A periodontitis (generalized)

    Hygiene instructions · Cleaning · OralDNA saliva test · Laser bacterial decontamination · MI Paste (remineralizing)

  7. Sep 18, 2024CleaningStage I, grade A periodontitis (molar/incisor)

    Cleaning · Laser bacterial decontamination · OralDNA saliva test

  8. Jul 11, 2024Cleaning

    Cleaning

  9. Apr 4, 2024Exam and cleaningHealthy gums

    Comprehensive exam · Bitewing x-rays · X-rays · Intraoral photos · Cleaning · Hygiene instructions

Genetics

My 23andMe and InsideTracker DNA results, a gum-inflammation gene from OralDNA, and two reports run on my raw 23andMe data: Genetic Genie for drug-metabolism and folate-cycle genes, and Promethease for single-variant findings.

How I process medications

SLCO1B1
Normal functionTypical statin handling; no gene-linked raised risk of statin muscle side effects.
CYP2C19
Intermediate metabolizerClopidogrel (Plavix) is likely less effective, worth knowing before any stent or clot treatment. Citalopram (Celexa): likely typical response.
DPYD
Normal metabolizerTypical handling of fluoropyrimidine chemotherapy drugs.
TPMT
Intermediate metabolizerOne copy of each half of TPMT*3A, the usual non-working TPMT allele in Europeans: intermediate metabolizer of thiopurine drugs (azathioprine, mercaptopurine, thioguanine). Not on the 23andMe report.
NAT2
Likely intermediate acetylatorOne slow-acetylator allele; with the next line, most likely an intermediate acetylator (isoniazid, hydralazine, sulfasalazine).
UGT1A1
Likely one Gilbert alleleLikely one copy of the Gilbert allele: bilirubin can run mildly high, harmless. Matters for irinotecan and atazanavir dosing.
CYP3A5
Non-expresser, the usual European typeTwo copies: CYP3A5 non-expresser, the usual state in Europeans. Standard tacrolimus dosing applies.

Typical: VKORC1 (warfarin) · CYP2B6 (efavirenz, bupropion, methadone) · NUDT15 (thiopurines) · ABCG2 (rosuvastatin, allopurinol) · OPRM1 (opioids, naltrexone) · G6PD (dapsone, primaquine) · MT-RNR1 (no aminoglycoside hearing risk) · Factor V Leiden (estrogen clot risk). Sources: 23andMe, and the GenVue report from the same raw data. Before azathioprine or another thiopurine, ask for TPMT-guided dosing.

Folate cycle and other enzymes

+/+ two copies of the variant, +/- one, −/− none. Most of these are common, with small or unproven effects; homocysteine, B12 and folate levels in Bloodwork say more than the genes.

GeneResultWhat it means
MTHFRC677T (rs1801133)+/-One copy of the common C677T variant: the enzyme runs at roughly 65% of typical. About 4 in 10 people of European ancestry carry one copy; usually harmless. Homocysteine is the blood test that shows whether it matters.
MTHFRA1298C (rs1801131)−/−No copies. Combined with one C677T copy this is the mildest MTHFR pattern.
MTRRA66G (rs1801394)+/-One copy of a very common variant in the enzyme that recycles vitamin B12 for the folate cycle; small effect at most.
MTRRR415T (rs2287780)−/−No copies; typical.
COMTV158M (rs4680)+/-Val/Met, the most common genotype: intermediate breakdown speed for dopamine, adrenaline and estrogens.
CBSC699T (rs234706)+/-One copy; small and inconsistent effects in studies (some link it to slightly lower homocysteine).
BHMTBHMT-02 (rs567754)+/-One copy of a common variant in a backup homocysteine-recycling enzyme; no established clinical effect.
Antioxidant and detox enzymes
GeneResultWhat it means
GSTP1I105V (rs1695)+/-One copy of the lower-activity Val allele of a glutathione enzyme; about half of Europeans carry it; weak, inconsistent links to disease.
SOD2A16V (rs4880)+/-Ala/Val, the most common genotype of the mitochondrial antioxidant enzyme; no clear clinical effect.
NQO1P187S (rs1800566)−/−No copies of the low-activity variant; typical.
EPHX1Y113H (rs1051740)−/−No copies; typical.
EPHX1H139R (rs2234922)+/-One copy of the higher-activity allele; no known practical effect.

Health predispositions

23andMe tested 40 conditions. These are the results that are not typical; a predisposition is a probability, not a diagnosis.

  • Hashimoto's diseaseThyroid antibodies are tracked under Bloodwork, Thyroid.
    Increased likelihood
  • Asthma
    Increased likelihood
  • Skin cancer (basal and squamous cell)Daily sunscreen; see Protocols, Skincare.
    Increased likelihood
  • Celiac diseaseA 2016 celiac blood screen (tTG-IgA) was negative; the bone workup in the doctor's plan repeats it.
    Slightly increased risk
  • Hereditary hemochromatosis (HFE)Iron markers are tracked under Bloodwork, Endurance.
    Variant detected, not likely at increased risk
  • Age-related macular degenerationZeaxanthin and lutein are in the supplement stack.
    Variant detected, not likely at increased risk

Variants not detected

BRCA1/BRCA2 (selected variants) · Late-onset Alzheimer's disease (APOE ε4) · MUTYH-associated polyposis · Parkinson's disease · Alpha-1 antitrypsin deficiency · Chronic kidney disease (APOL1) · Familial hypercholesterolemia · G6PD deficiency · Hereditary amyloidosis (TTR) · Hereditary thrombophilia

Typical likelihood

anxiety, atrial fibrillation, coronary artery disease, diverticulitis, eczema, fibromyalgia, gallstones, glaucoma, gout, HDL cholesterol, high blood pressure, irritable bowel syndrome, kidney stones, LDL cholesterol, migraine, nonalcoholic fatty liver disease, obstructive sleep apnea, psoriasis, restless legs syndrome, rosacea, severe acne, melanoma, triglycerides, type 2 diabetes

Gum inflammation gene

C/GIL-6, position −174 (rs1800795)

Intermediate risk of gum inflammation

OralDNA's MyPerioID test. The G allele is linked to more IL-6 production, which also drives bone resorption. Tested Sep 2024.

Carrier status

  • Cystic fibrosis · variant detected
  • Rhizomelic chondrodysplasia punctata type 1 · variant detected

Not a carrier for the other 43 conditions tested. Carrier status means one copy of a recessive variant: no effect on my own health, relevant only to children's.

Single-variant findings (Promethease)

25,314 genotypes matched to SNPedia, Feb 2023. Promethease reads single SNPs from SNPedia and scores how interesting each is, not how risky. Most hits are common variants with small effects; 23andMe's many-variant models are the better guide where the two differ (hair loss, type 2 diabetes, fatty liver).

Worth knowing

  • Type 2 diabetes (TCF7L2) (T;T)Two copies of the strongest common type 2 diabetes risk allele, about twice the odds of no copies; from the GenVue report. Glucose and HbA1c are the readout, and both stay normal.
  • Hereditary hemochromatosis (HFE H63D) (G;G)Two copies of the mild H63D iron variant. Without C282Y (absent: rs1800562 G;G) iron overload is uncommon; SNPedia's "likely affected" overstates it. Iron markers are the check.
  • Coronary artery disease (9p21) (C;G)One copy of the common 9p21 heart-risk allele, carried by about half of Europeans; SNPedia says 1.5x, large studies about 1.2 to 1.3x for one copy.
  • Type 2 diabetes (CDKAL1) (C;G)One copy of a common risk allele; about 1.1 to 1.2x per copy in large studies.
  • Type 2 diabetes and fasting glucose (MTNR1B) (C;G)One copy of a melatonin-receptor variant linked to slightly higher fasting glucose.
  • Obesity (FTO) (C;T)One copy of the common FTO weight allele; about 1.2x odds per copy in large studies (SNPedia says 1.67x).
  • Crohn's disease (ATG16L1 T300A) (C;C)Two copies of a common Crohn's risk allele (about 1.5 to 2x on a low baseline), partly offset by the protective IL23R variant.
  • Thyroid hormone conversion (DIO1) (A;A)Common genotype linked in one 2008 study to a slightly lower T3-to-T4 ratio; the effect on lab values is small.
  • Pattern hair loss (20p11) (T;T)Two copies of a common hair-loss allele (about 2x in one study); 23andMe's many-variant model says early hair loss is unlikely.
  • Several cancers (ATM) (T;T)Two copies of a common ATM variant tied to cancer risk in small studies; weak evidence.

In my favor

  • Autoimmune protection (IL23R R381Q) (A;G)One copy of a well-replicated protective variant: lower risk of Crohn's disease, psoriasis and ankylosing spondylitis.
  • Macular degeneration (CFH) (C;C)No copies at a marker for the main CFH risk allele (Y402H); SNPedia: 0.34x risk. Fits 23andMe's "not likely at increased risk".
  • Obesity and metabolic syndrome (MC4R V103I) (A;G)One copy of a protective appetite-gene variant: modestly lower obesity risk.
  • Bone density (WNT16) (T;T)Two copies of a stronger-bone allele; a second WNT16 SNP (rs2707466) agrees, though two other bone SNPs point the other way.
  • Progressive supranuclear palsy (MAPT H2) (A;G)One copy of the MAPT H2 haplotype: lower risk of this rare brain disease, and in some studies of Parkinson's.
  • HDL cholesterol (CETP) (A;G)Associated with higher HDL cholesterol.
  • Alzheimer's onset (CCL11) (A;G)Linked to later Alzheimer's onset in one study; weak evidence.

Where the reports overlap with 23andMe, the genotypes agree: APOE e3/e3, HFE H63D with no C282Y, the BRCA founder variants absent, CYP2C19, SLCO1B1, DPYD, G6PD, factor V Leiden, both carrier results and the traits.

InsideTracker DNA estimates

Polygenic estimates of where my genes push each trait, January 2023. My measured values are in Bloodwork.

  • BMI and weight gain (single variant)
  • Weight loss on a low-fat diet
  • Caffeine consumption
  • Sleep duration (longer)
  • Blood pressure
  • Vitamin B12 (higher levels)
  • Lower calcium
  • White blood cell count (higher)
  • hsCRP (higher)
  • Gluten intolerance
  • Peanut allergy
  • Fasting glucose
  • HDL cholesterol
  • Triglycerides
  • Weight gain on a high saturated fat diet
  • Magnesium
  • Vitamin D
  • Endurance and power
  • Total and free testosterone
  • Hemoglobin
  • Lactose intolerance
  • Total cholesterol
  • LDL cholesterol
  • GGT

Ancestry

99.5% European

  • British and Irish73.5%
  • French and German23.2%
  • Broadly Northwestern European1.5%
  • Ashkenazi Jewish0.7%
  • Eastern European0.6%
  • Western Asian and North African0.4%
  • Unassigned0.1%
Maternal haplogroup
T2a1a
Paternal haplogroup
E-V13

Wellness and traits

Alcohol flush
Unlikely to flush
Caffeine consumption
Likely to consume more
Deep sleep
Less likely to be a deep sleeper
Genetic weight
Predisposed to weigh less than average
Lactose intolerance
Likely tolerant
Muscle composition
Common in elite power athletes
Nearsightedness
Increased likelihood
Cat allergy
Increased likelihood
Dog allergy
Increased likelihood
Saturated fat and weight
Likely similar weight
Seasonal allergies
Typical likelihood
Sleep movement
Likely average or less movement
Eye color
Likely blue or green
Hair
Likely dark, straight or wavy, less likely thick
Freckles
Likely a lot
Early hair loss
Likely none
Earwax
Likely wet
Bitter taste
Likely can't taste
Asparagus odor
Likely can smell
Cilantro aversion
Slightly higher odds of disliking
Sweet vs. salty
Likely prefers salty
Photic sneeze reflex
Likely
Wake-up time
Likely around 8:16 AM
Mosquito bites
Likely bitten more often
Fear of public speaking
More likely
Musical pitch matching
Less likely

A selection of the 37 trait reports; the full list is in the 23andMe report.

Medications

Current prescriptions, with dose and frequency.

MoleculeDoseFrequency
Acarbose100 mgEach meal
Atorvastatin5 mg3x / wk (may drop to 2x / wk)
Ezetimibe5 mgMost days
Metformin XR500 mg2x daily
Rapamycin (Sirolimus)4 mg1x / wk
Tadalafil2.5 mgEvery other day

Current investigations

Interventions I am researching but have not adopted.

  • 17α-estradiol 8 mg/wk transdermal · For slowing aging and reducing all-cause mortality.
  • Finasteride 1 mg · For prostate health and cancer risk reduction.
  • Telmisartan 80 mg · For the blood pressure benefits of angiotensin II receptor blockers.
  • Canagliflozin 100 mg / empagliflozin 10 mg · For SGLT2 inhibitor benefits on blood sugar, blood pressure, and risk of heart and kidney disease.
  • Tirzepatide 1 mg · For GLP-1 agonist and GIP analogue benefits on blood sugar, blood pressure, and risk of heart and kidney disease.
  • Low-dose naltrexone 4.5 mg · For immune system modulation and reducing inflammation-induced aging.

Supplements

Everything I take, with the brand, the dose, and morning and evening counts. Filter by name, molecule, or brand.

43 of 43

SupplementDoseMorningEvening
AkkermansiaPendulum Glucose Control
  • 1 billion AFU · Proprietary probiotic blend (Clostridium butyricum WB-STR-0006, Clostridium beijerinckii WB-STR-0005, Anaerobutyricum hallii WB-STR-0008, Akkermansia muciniphila WB-STR-0001, Bifidobacterium infantis), chicory inulin and oligofructose
11
AstaxanthinDeva Astaxanthin Super Carotenoid
  • 12 mg · Astaxanthin
1
B ComplexThorne Methyl Guard Plus
  • 90 mg · B2 Riboflavin (as Riboflavin 5'-Phosphate Sodium)
  • 45 mg · B6 Pyridoxine (as Pyridoxal 5'-Phosphate)
  • 5 mg · B9 Folate (3mg as L-5-Methyltetrahydrofolate, from L-5 Methyltetrahydrofolic Acid, Glucosamine Salt)
  • 3 mg · B12 Methylcobalmin
  • 1800 mg · Betaine Anhydrous (Trimethylglycine)
3
BerberineDoNotAge Pure Berberine
  • 500 mg · Berberine
1
Black CurrantSwanson Full Spectrum Black Currant
  • 400 mg · Black Currant Fruit (Ribes nigrum)
1
BoronLife Extension Boron
  • 3 mg · Boron (as boron citrate / aspartate / glycinate complex)
  • 25 mg · B2 Riboflavin
1
Broccoli SulforaphaneJarrow Broccomax Mirosinase Activated SGS
  • 17.5 mg · Sulforaphane Glucosinate (from Broccoli Seed Extract [Brassica oleracea L. Italica] [Standardized to 3.5% SGS], Myrosinase Enzyme
1
Butyric AcidTesseract ProButyrate Sustained Release
  • 600 mg · Natural Butyric Acid
2
CNow C-500
  • 500 mg · Vitamin C (from Calcium Ascorbate)
  • 55 mg · Calcium (from Calcium Ascorbate)
  • 10 mg · Citrus Bioflavonoid Complex
1
Ca-AKGProhealth Longevity Calcium AKG Longevity
  • 1000 mg · Calcium Alpha Ketoglutarate
22
Cocoa FlavanolsCocoaVia Cardio Health
  • 1130 mg · Cocoapro Cocoa Extract (Bean)
  • 500 mg · Cocoa Flavanols
  • 85 mg · of which is (-)-epicatechin
  • 25 mg · Caffeine (naturally occurring)
2
CoQ10Doctor's Best High Absorption CoQ10 with BioPerine
  • 100 mg · Coenzyme Q10 (Ubiquinone)
1
CreatineLife Extension Creatine Capsules
  • 3000 mg · Creatine monohydrate
  • 33 mg · Vitamin C (as ascorbyl palmitate)
6
CurcuminLife Extension Curcumin Elite
  • 500 mg · Curcumin Elite Proprietary CGM Blend
  • 200 mg · 40% curcuminoids [from turmeric (rhizome)]
  • 15 mg · 3% turmerones [from turmeric (rhizome)]
  • 150 mg · 30% galactomannans [from fenugreek (seed)]
1
D-3Doctor's Best Vegan D3 2500 IU with Vitashine D3
  • 62.5 mcg (2500 IU) · Vitamin D3 (as cholecalciferol) (Vitashine D3)
11
DHEACountry Life DHEA
  • 25 mg · Dehydroepiandrosterone (DHEA)
1
ENow Vitamin E-Oil d-alpha Tocopherol
  • 85 mg · Vitamin E (as d-alpha Tocopherol)
4 drops
FisetinLife Extension Bio-Fisetin
  • 44.5 mg · Bio-Fisetin Proprietary Blend
  • 8 mg · 18% fisetin [from wax tree extract (stem)]
  • 15 mg · 35% galactomannans [from fenugreek (seed)]
1
GarlicLife Extension Optimized Garlic
  • 2400 mg · Garlic extract (bulb) [std. to 10,000 ppm allicin potential]
44
Garlic, Aged KyolicWakunaga Kyolic Aged Garlic Extract
  • 1200 mg · Aged Garlic Extract Powder (bulb)
44
GenisteinSwanson Genistein from Sophora Japonica, Soy Free
  • 125 mg · Genistein (Sophora japonica) (fruit)
1
Ginger RootSpring Valley Ginger Root
  • 1100 mg · Organic ginger root (zingiber officinale)
2
Glucosamine Chondroitin MSMDoctor's Best Vegan Glucosamine Chondroitin MSM
  • 1500 mg · Glucosamine Hydrochloride Potassium Sulfate (GreenGrown Glucosamine)
  • 1000 mg · MSM (Methylsulfonylmethane) (OptiMSM)
  • 600 mg · Chondroitin Sulfate (from chondroitin sulfate sodium) (Mythocondro)
  • 180 mg · Chloride (from glucosamine hydrochloride potassium sulfate)
  • 65 mg · Sodium (from chondroitin sulfate sodium)
  • 200 mg · Potassium (from glucosamine hydrochloride potassium sulfate)
44
GlycineLife Extension Glycine
  • 1000 mg · Glycine
1
TMG (Beta Anhydrous Trimethylglycine)Life Extension TMG
  • 1000 mg · Trimethylglycine (TMG) (as beta anhydrous)
2
Hyaluronic AcidDEVA Hyaluronic Acid
  • 300 mg · Hyaluronic Acid (from Sodium Hyaluronate)
3
IodineSwanson Kelp
  • 225 mcg every other day · Iodine (from kelp)
  • 56 mg every other day · Atlantic Kelp (ascophyllum nodosum) (standardized to 0.4% iodine)
1 every other day
KThorne Vitamin K
  • 1 mg · K1
  • 5 mg · K2 (as MK-4)
  • 90 mcg · K2 (as MK-7)
1
L-LysineSpring Valley L-Lysine
  • 1000 mg · L-Lysine (as L-Lysine Hydrochloride)
11
Lithium OrotateLife Extension Lithium
  • 1 mg · Lithium (as lithium orotate)
1
Lycopene21st Century Lycopene
  • 25 mg every other day · Lycopene
  • 170 mg · Calcium (as calcium carbonate)
1 every other day
MagnesiumDEVA Magnesium Glycinate with Trace Minerals
  • 300 mg · Magnesium (from Magnesium Bisglycinate)
  • 30 mg · Trace Minerals (from Utah Inland Sea)
1
Myo-inositolLife Extension Inositol Caps
  • 1000 mg · Inositol [as myo-inositol]
1
NACLife Extension N-Acetyl-L-Cysteine
  • 1800 mg · N-acetyl-L-cysteine
3
NRTru Niagen
  • 300 mg · Niagen (nicotinamide riboside chloride)
2
Omega 3 (DHA/EPA/DPA) & Omega-7DEVA Omega-3 DHA-EPA 300 mg
  • 587 mg · DHA (docosahexaenoic acid)
  • 368 mg · EPA (eicosapentaenoic acid)
  • 75 mg · DPA (docosapentaenoic acid)
  • 0.9 mg · Omega 7 (palmitoleic acid)
3
Omega 3 (ALA)DEVA Vegan Flaxseed Oil
  • 500 mg · Flaxseed Oil (organic) (Typically providing 55% Alpha Linolenic Acid)
1
Psyllium HuskYerba Prima, Psyllium Husks Veg Caps
  • 5000 mg · psyllium
4 (with meal)4 (with meal)
SpermidineNutricost Spermidine Wheat Germ
  • 1000 mg · Wheat germ extract (Triticum) (germ) (1% spermidine) (equivalent to 10 mg spermidine)
  • 0.5 mg · Thiamin (as thiamine hydrochloride)
  • 3 mg · Zinc (as zinc citrate)
2
TaurineNow Double Strength Taurine
  • 2000 mg · Taurine (free-form)
2
Urolithin ATimeline Mitopure Powder
  • 500 mg · Urolithin A
1
Zeaxanthin & LuteinSports Research Lutein + Zeaxanthin
  • 20 mg every other day · Lutein (from marigold extract [tagetes spp.]) (flower) (Lute-gen)
  • 4 mg every other day · Zeaxanthin (from marigold extract [tagetes spp.]) (flower) (Lute-gen)
1 every other day
Zinc & CopperJarrow Zinc Balance
  • 15 mg · Zinc (as zinc L-Methionine Sulfate)
  • 1 mg · Copper (as gluconate)
1

Reading

The papers behind the lipid and longevity parts of the regimen.

  1. Association of triglyceride-lowering LPL variants and LDL-C-lowering LDLR variants with risk of coronary heart disease

    Ference BA, et al. · JAMA, 2019

    ApoB, not the cholesterol number, is the unit of heart risk.

  2. Eradicating the burden of atherosclerotic cardiovascular disease by lowering apolipoprotein B lipoproteins earlier in life

    Robinson JG, et al. · Journal of the American Heart Association, 2018

    The case for lowering ApoB decades early.

  3. Moderate-intensity statin with ezetimibe versus high-intensity statin monotherapy in atherosclerotic cardiovascular disease

    Kim BK, et al. (RACING) · The Lancet, 2022

    A low statin dose plus ezetimibe matches a high statin dose, with fewer side effects.

  4. Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice

    Strong R, et al. · Aging Cell, 2022

    The mouse evidence behind taking rapamycin and acarbose together.

  5. The quest to slow ageing through drug discovery

    Partridge L, Fuentealba M, Kennedy BK · Nature Reviews Drug Discovery, 2020

    A review of the drug candidates most of my regimen comes from.

Vaccines

My full immunization record, grouped by series.

Covid-19

  • Mar 2021 · 0.5mL Moderna mRNA LNP-S PF, Lot #027A, CVS Pharmacy #9145
  • Apr 2021 · 0.5 mL Moderna mRNA LNP-S PF, Lot #039A21A, CVS Pharmacy #9145
  • Oct 2021 · 0.3 mL Pfizer mRNA LNP-S PF, Lot #FH8020, CVS Pharmacy #3068
  • Sep 2022 · 0.5 mL Moderna bivalent, Lot #AS7144B, CVS Pharmacy
  • Dec 2022 · 0.3 mL Pfizer, Walgreens Pharmacy #12143
  • Oct 2023 · 0.5 mL Moderna Spikevax Cov2 updated XBB.1.5, SRS Sorrento Mesa
  • Oct 2025 · 0.5 mL Moderna Spikevax 2025-26, Lot #3052786, Sharp

DTP (Diphtheria, Tetanus, Pertussis)

  • Nov 1991 · DTP
  • Jan 1992 · DT
  • Mar 1992 · DTP
  • Sep 1993 · DTP
  • May 1996 · DTP

Hib (Haemophilus influenzae type b)

  • Nov 1991
  • Jan 1992
  • Mar 1992
  • Mar 1993

Hepatitis A

  • Jul 2010 · Hep A ped/adol Lot #AHAVB349BA
  • May 2012 · adult Lot #AHAVB456AA

Hepatitis B

  • Mar 1993
  • Apr 1993
  • Sep 1993
  • Aug 2024 · adult booster Heplisav-B (HepB-CpG), Lot #944918, Sharp

HPV

  • Dec 2015 · UCSD SHS
  • Jan 2016 · UCSD SHS
  • Aug 2016 · UCSD SHS

Influenza

  • Jan 2003 · IIV3 HIst
  • Jan 2013 · Intradermal IIV3 P-free, MSU Health
  • Jan 2015 · ccIIV3 Flucelvax Pfree Lot #017011A, MSU Health
  • Oct 2017 · inactivated, UCSD Student Health
  • Feb 2020
  • Oct 2020
  • Oct 2021
  • Sep 2022 · 0.5 mL Sanofi-Pasteur Fluzone Quad Lot #UT7683JA CVS Pharmacy
  • Dec 2022 · trivalent, SRS Del Mar
  • Dec 2022 · quadrivalent MDCK pfree, Walgreens Pharmacy #12143
  • Sep 2023 · quadrivalent pfree, SRS Sorrento Mesa
  • Aug 2024 · trivalent pfree Fluzone, Lot #UT8408KA, Sharp
  • Jan 2025 · trivalent MDCK pfree Flucelvax, Lot #946619, Sharp
  • Oct 2025 · 0.5 mL trivalent pfree, GSK, Lot #5R4CY, Sharp

Meningococcal

  • Feb 2008 · MenACWY-D Menactra Lot #PU2403AA

MMR (Measles, Mumps, Rubella)

  • Dec 1992
  • May 1996

Orthopoxvirus (Monkeypox)

  • Jul 2022 · Jynneos, North Central Public Health Center, Lot #FDP00002
  • Sep 2022 · Jynneos, County of San Diego Immunization Program, Lot #FDP00014

Polio

  • Nov 1991 · OPV
  • Jan 1992 · OPV
  • Mar 1992 · OPV
  • Sep 1993 · OPV
  • May 1996

Td, Tdap (Diphtheria, Tetanus, Pertussis booster)

  • Sep 2003 · Td adult adsorbed
  • Jul 2009 · Tdap adol/adult Lot #AC52B036BA
  • May 2011 · Tdap adol/adult Lot #C3540AA
  • Oct 2017 · Tdap, Beach Area Family Health Center

Tuberculosis

  • Sep 2003 · TST-PPD Intradermal

Varicella (Chicken pox)

  • Sep 1995 · Varivax
  • Jul 2010 · Varivax Lot #0069Z

Immunity blood tests

  • Feb 18, 2016 · Hepatitis A antibody: Reactive (immune)
  • Feb 18, 2016 · Hepatitis B surface antibody: 93 mIU/mL (immune (10 or more))
  • Feb 12, 2020 · Hepatitis B surface antibody: Immune (immune)

Skincare

Morning

  • SkinCeuticals C E Ferulic serum

    SkinCeuticals C E Ferulic

    • 15% L-ascorbic acid
    • 1% alpha tocopherol
    • 0.5% ferulic acid
  • Skin Aqua UV Super Moisture Gel SPF 50+

    Skin Aqua UV Super Moisture Gel SPF 50+ PA++++

    • Ethylhexyl methoxycinnamate (sunscreen)
    • Bis-ethylhexyloxyphenol methoxyphenyl triazine (bemotrizinol) (sunscreen)
    • Diethylamino hydroxybenzoyl hexyl benzoate (sunscreen)
    • Ethylhexyl triazone (sunscreen)

Evening

  • Curology custom compounded formula

    Curology custom compounded formula

    • Tretinoin 0.05%
    • Tranexamic acid 5%
    • Niacinamide 4%
  • Topical rapamycin 0.1%

    Topical rapamycin 0.1%

  • La Roche-Posay Toleriane Double Repair face moisturizer

    La Roche-Posay Toleriane Double Repair face moisturizer

    • Prebiotic thermal water
    • Glycerin
    • Ceramide-3
    • Niacinamide

Diet

I subscribe to a vegan, plant-based diet. Unless I'm out to eat with friends, most of what I eat is delivered to my door by Thistle. My daily meals look something like the following.

Breakfast · 6:00 AM

Brownie batter smoothieMatcha chia smoothieBlue wildflower smoothieChunky monkey smoothie

One Thistle plant-based breakfast smoothie

  • 250–400 calories on average
  • 100% plant ingredients by weight
  • 10g+ of plant protein
  • ~10g of fiber
  • 0.5–1 oz of nutrient-dense booster foods

Lunch · 11:30 AM

Pinto bacon ranch potato saladMuffuletta saladRamen saladFalafel salad

One Thistle plant-based lunch salad

  • 450–650 calories on average
  • 100% plant ingredients
  • 20g+ of plant protein from legumes, nuts and seeds, adashah, tempeh, tofu, and whole, ancient grains
  • ~15g of digestion-promoting fiber
  • 2–4 cups of leafy greens and other vegetables
  • 0.5–1 oz of nutrient-dense booster foods such as spirulina, dandelion root, turmeric, chia, ashwagandha, or reishi

Dinner · 4:00 PM

Blue lagoon falafel bowlMoroccan tagine bowlCrunchy Thai peanut bowlRoasted artichoke scampi

One Thistle plant-based dinner bowl

  • 450–650 calories on average
  • 100% plant ingredients
  • 20g+ of plant protein from legumes, nuts and seeds, adashah, tempeh, tofu, and whole, ancient grains
  • ~15g of digestion-promoting fiber
  • 2–4 cups of leafy greens and other vegetables
  • 0.5–1 oz of nutrient-dense booster foods such as spirulina, dandelion root, turmeric, chia, ashwagandha, or reishi

Exercise

Historically, I got the majority of my exercise from walking my dogs around the block and cycling with my partner, outdoors in San Diego or indoors on Zwift.

After a DEXA scan in May 2024 revealed osteopenia, I switched to rucking (walking with a weighted backpack) to increase bone density. I have also added a three-day-per-week strength training program to increase muscle mass and bone density.

Gear

  • GORUCK Rucker 4.0 backpack in armor grey and coyote

    GORUCK Rucker 4.0 backpack · 20L, with padded hip belt

  • Xero Zelen shoe

    Xero Zelen shoes · sustainable cork, zero-drop, wide toebox

  • Dexcom G7, the sensor I wore before switching to the Stelo

    Dexcom Stelo continuous glucose monitor · switched from the Dexcom G7 in 2026

Sleep

Average bedtime
9:50 PM
Average wakeup
6:05 AM
Time to fall asleep
<15 min
Time to get up
<1 min
Average snoring
48 min
Average resting heart rate
48–52 bpm
Average HRV
42–52 ms
Average respiratory rate
13.1–16.1 breaths / min

Gear

  • Eight Sleep Pod 3

    Eight Sleep Pod 3

  • Eye shade

  • Breathe Right nose strips

Oral care

Dental stats

  • Dental cleanings 4x per year
  • Never had a cavity
  • Invisalign and cosmetic bonding in 2017
  • Lumina Probiotic in June 2024

Routine

  • Water floss with Waterpik Sidekick · 2x per day

  • Wax floss with Slate Electric Flosser · 2x per day

  • Brush with Oral-B Genius iO Series 10 electric toothbrush · 2x per day

    • Morning toothpaste: LIVFRESH gel toothpaste with edathamil
    • Evening toothpaste: Something Nice Zero Pro toothpaste with 10% nanohydroxyapatite
Waterpik Sidekick water flosserOral-B Genius iO Series 10 electric toothbrushLumina Probiotic